Amazing! This guy writes about science and what scientists do for the lay reader without coming off as an arrogant arse. He makes the point that science is not a conglomeration of lifeless facts. Science, as an act, a career, a way of life, comes from questions, and questions come from ignorance. He's trying to get his students and all of us to see the excitement in science, the discovery potential. He's very anti-hypothesis, but the truth is, few working experiments actually start with a hypothesis -- that's for 7th grade science tests.
The case studies in the second half of the book were the strongest part. Chapters 3 and 4 were a little weak, a little harder to read than the rest of the book. But the books makes perfect sense, so if you're short on time or patience, I'd recommend skipping those.